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Biology 30

Unit 1 The Chemical Basis of Life

Unit Overview

This unit highlights the basic chemistry which the student needs to understand the complex biochemical processes which occur in the cells and in the organs of organisms. The major biochemical processes; polymerization, enzyme catalysis and inhibition, DNA replication, and the transcription of RNA are described.

The teacher should check the entry level of the students to determine the extent to which the basic chemistry of bonds and bond energies should be discussed. Activities 2, 3, and 4 should be done or other comparable activities should be used in their place. These activities demonstrate the chemistry of bands and band energies.

Conceptual Development

The Conceptual Development section will be updated to reflect changes to K-10 Science curricula.
See Figure 10.

Note: A pre-assessment to determine the entry level of the students may be appropriate.

Key Concepts

Bond energy, catalysis, inhibition, molecular structure.

Webbing Highlights

Safety Concerns

Normal laboratory safety procedures should be followed. Review the safety section in this Guide and in the Science Program Overview and Connections K-12 document. Students must be reminded to never taste any materials that are being used in the lab oratory.

If tasting is required as a part of an activity, there should be clear guidelines established about how the tasting is done, and under what conditions it takes place.

Science-Technology-Society-Environment (S T S E) Focus

Factors of Scientific Literacy Which Should be Emphasized

Common Essential Learnings Foundational Objectives to Emphasize

CCT To develop an understanding of how knowledge is created, evaluated, refined, and changed within biology.
COM To enable students to understand and use the vocabulary, structures and forms of expression which characterize the study of science.
IL To develop students' abilities to access knowledge.

Biology Foundational and Learning Objectives

  1. Appreciate the basic principles of chemistry which are involved in life processes.

    1.1 Recognize that organisms are made of atoms.
    1.2 Realize the relationship between the electron structure of atoms and the type of bond which forms.
    1.3 Understand the relationship between chemical bonds and stored energy.
    1.4 Recognize the importance and ongoing nature of various chemical reactions in the body.
    1.5 Discuss a chemical reaction Ä the reactants, products and energy either required or produced.
    1.6 Illustrate with examples the similarities and differences between synthesis and decomposition reactions.
    1.7 Describe some relationships which exist between synthesis and decomposition reactions in relation to the functioning of the body ie., dynamic balance (homeostasis).

  2. Investigate the properties of carbohydrates, lipids, and proteins.

    2.1 Explain how carbon-based molecules interact with each other through hydrogen bonding.
    2.2 Compare mono-, di-, and polysaccharides and then provide examples of their usefulness to a living system.
    2.3 Describe the relationship between fatty acids and fats by providing examples to illustrate when they are useful to a living system.
    2.4 Describe the relationship between amino acids and proteins with reference to the peptide bond.
    2.5 Discuss enzymes using a series of key words which should be included in a concept web with the heading of proteins. (The key words are substrate, enzymeÄsubstrate complex, lock and key, catalyst, factors affecting enzyme activity [temperature; relative concentration of substrate], enzymes, and coenzymes.)
    2.6 Indicate the component parts of a fat molecule.
    2.7 Recognize the value of proteins by using examples from the human body.

  3. Describe the structure of nucleic acids.

    3.1 Describe the similarities and differences in the structure of DNA and RNA.
    3.2 Describe the processes of replication and transcription.

Assessment Techniques

Suggested Activities and Inquiries

Note: Many activities have been identified in the key resources Information Bulletin.

  1. Basic body compounds.

    This activity allows students an opportunity to practice some laboratory techniques and to also learn something about the identification of three categories of basic materials that are required the body.

    Objectives: 2.0
    Factors: B11, C15, E7, COM
    Assessment: Short-Answer Quiz/Test;

    Laboratory Report

    Instructional Strategies

    a) Use the chart below as a guide:

    b) Place students in pairs and assign tasks such as equipment manager and recorder.

    c) Remind students about general safety procedures when working with chemicals in a laboratory.

    d) Conduct these tests. Discuss the results.

    e) Test a variety of foods for the presence of simple sugars, starch, protein, and fat. (Consider comparing traditional foods of Aboriginal peoples to a modern diet.)

    Evaluation strategy

    The students should turn in their lab sheets and write a short quiz on how to test for various compounds.

    Kinds of Compounds

    Results

    Carbohydrates - Glucose Test


    - Starch Test


    Protein Test


    Fat Test


  2. Have student lab groups construct models of specific organic chemicals from molecular model kits. If each group does a different molecule (or several), a class set of representative models can be produced quickly. Each group might be asked to prepare a description of the chemical and its function for presentation to the class. Molecules that could be assigned are glucose, fructose, sucrose, lactose, alanine, phenylalanine, butanoic acid, any triglyceride, any dipeptide, and so on. Posters, animation, role plays, videos, etc. may be used here, too.

  3. For each lab group, prepare four gelatin plates, by pouring hot gelatin into a Petri dish, and cooling. On one plate, place a cube of freshly cut pineapple, and on another a cube of freshly cut apple. The third and fourth plates should get a cube of canned pineapple and a pinch of meat tenderizer containing papain, respectively. The effect of each on the gelatin over the course of ten to fifteen minutes, and then at the next class period, should be recorded. Why is papain used in some beauty product s?

  4. Ask each group to add to a 13 x 100 mm test tube containing 3 mL of 3% hydrogen peroxide, a small cube of freshly cut turnip. To another test tube, add a similar sized cube of freshly cut potato. Compare the reactions in the two test tubes. Sense the temperature. What other foods can be found which act similarly to the turnip? to the potato?

  5. Have students make a list of the foods that they consume for one week under the heading of carbohydrates, fats and proteins. Have students attempt to decide which foods have been processed and in what way they have been processed. Finally, attempt to decide which foods could be processed less or not at all. (Be aware of the topic of anorexics and/or bulemics.)

  6. Invite a guest speaker to discuss the nutritional effects of certain favourite things we eat.

  7. Brainstorm a list of foods students eat. Have students investigate two foods:

  8. Try Activity 11 page 100 for this unit.

  9. Was topic C-2 "Food Additives and Human Nutrition" covered in the new grade 10 Science course? Use certain objectives or review what was covered(?).

  10. Compare historical and contemporary diets in relation to fats and cholesterol levels.

  11. Act out replication and transcription (objective 3.2) or use some other type of simulation. See Activity 11 in Unit 30-3.

  12. Do a study of heart disease and relate that to harmful fatty acids.

  13. What kind of research is being done with nucleic acids? What is the impact of this research on society?

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